NFL Week 1 is here! Check out updated NFL odds and picks for the top overlay and underlay favorites. Also, check out the top dark horse moneyline and top dark horse against the spread picks for the first week in the 2020 season so you can place your bets against their NFL odds!  

Week 1 Odds, Picks, Favorites & Dark Horses | 2020 NFL Update

  • When: Thursday, Sep. 10 – Monday, Sep. 14

Top NFL Week 1 Odds Favorites to Back

Top Favorite to Back: Kansas City Chiefs -9 ½ versus Houston Texans

9 ½ seems like a ton of points. This season’s Houston Texans squad isn’t close to the one that scored 24 points against the Chiefs in the playoffs last season. Deshaun Watson will be without security blanket, while Houston’s defense is a mess. 

Sure, J.J. Watt will play strong like he does every time he steps onto the field. The rest of the front seven won’t protect J.J. from double-teams. If the Texans can’t pressure Mahomes, they won’t stop the Chiefs from scoring points on every drive.

Top Favorite to Stay Away From: Baltimore Ravens -7 ½ versus Cleveland Browns

Nobody knows for sure if Lamar Jackson is one-hundred percent. The 2019 MVP suffered a groin injury. Groin injuries are notorious for taking a long time to heal. Not only that, but the Browns are a much better team this season.

The offense should rock it unless Baker Mayfield simply doesn’t know how to play quarterback in the NFL. The defense could be a top five unit if free agent additions Andrew Sendejo, Karl Joseph, and Sheldon Richardson step it up.

That doesn’t mean Cleveland beats the Ravens. It does mean the Browns should keep this closer than the number. 

Top Dark Horse to Back: Arizona Cardinals +255 moneyline versus San Francisco 49ers

The 49ers should be one of the best teams in the NFC. In this game, though, the Niners will find it difficult to stop the Cardinals from scoring at least 28. Arizona’s offense should be on of the top units in the NFL. 

On Sep. 8, the Cards signed DeAndre Hopkins to a two-year extension. With a happy Hopkins playing on the opposite side of Fitzgerald, Christian Kirk in the slot, and a backfield that includes Murray, Kenyan Drake, and Chase Edmonds, few teams will stop Arizona from scoring TD after TD.

Expect the offense to hang 28 to 35 onto the 49ers. If that happens, the Desert Birds should be close enough in the fourth quarter to challenge for the straight up win.

Top Dark Horse to Back ATS: New York Giants +6 versus Pittsburgh Steelers

Sure, the G-Men won’t play in front of fans. No worries. The Giants are still a home team giving up 6 points to a squad with a quarterback that hasn’t played in a year. Yes, the Steelers are the better team. 

But are they good enough to beat the New York Giants by 7? New York will field an improved offense and improved defense. Don’t be surprised if quarterback Daniel Jones pulls a Carson Wentz in his second season in the NFL. Jones has the tools to make the Giants an 8-8 squad.

When it comes to the Week 1 matchup, Pittsburgh’s defense won’t contain a motivated Saquon Barkley while Jones has a much better offensive line to protect him. The defense is also better than it has been in years. The Giants can make this a field goal game.


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